Let us go through Zollinger-Ellison Syndrome symptoms, treatment and pictures to get a clear understanding of the disease.
Zollinger-Ellison Syndrome symptoms
ZES symptoms are known to be similar to the ones in peptic ulcers and can include
1. Searing abdominal pain
2. Diarrhea
3. Nausea, vomiting
4. Intense gastroesophageal reflux-a disorder where foods from the stomach and food can cause clogging in the esophagus.
Zollinger-Ellison Syndrome Treatment
ZES treatment can be done with drugs that can treat symptoms of ulcer. If possible, there may be surgery advisable to remove tumors. In some cases, chemotherapy is used when the tumors are too strong to remove with the help of surgery. There is a category of drugs known as proton pump inhibitors that can comprehensively reduce gastic acid buildup in the stomach. Some of the drugs included in this type of medication are
• esomeprazole (Nexium)
• lansoprazole (Prevacid)
• pantoprazole (Protonix)
• omeprazole (Prilosec)
• 5-fluorouracil (Adrucil)
• doxorubicin (Doxil)
• streptozotocin (Zanosar)
Information on Zollinger-Ellison syndrome (ZES)
Zollinger-Ellison Sydrome is a rare disorder that is identified by tumors called ‘gastrionmas’ that build up in the duodenum, pancreas or both. These gastrinomas can cause gastric acid to build up excessively leading to ulcers in the duodenum. Though any one can get ZES, it is more common in the case of men among 30 and 50 years or in people who have a genetic disorder called multiple endocrine neoplasia type 1 (MEN1). To diagnose ZES, the doctor measures stomach acid and the gastrin circulating in the blood by performing imaging tests to identify gastrinomas. The survival rate of people with ZES can depend on the nature and extent of the disease. 25 percent of the cases are known to be cancerous.
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